The Obstetric Face and Challenge of HIV/AIDSGUIDOZZI, FRANCO MBBCh, FRCOG, FCOG*; BLACK, VIVIAN MBBCh, BSc, DTMH, HIV Man Dip†Clinical Obstetrics & Gynecology: June 2009 - Volume 52 - Issue 2 - pp 270-284 doi: 10.1097/GRF.0b013e3181a4f365 Obstetric Practice in the Third World Abstract Author Information The human immunodeficiency virus (HIV) pandemic is one of the most serious health crises facing the world. Of the estimated 33.2 million people living with HIV worldwide, 22.5 million (68%) live in Sub-Saharan Africa, where women of childbearing age are most severely affected. Children primarily acquire HIV infection through mother-to-child transmission. Despite recent encouraging success, low-income countries have not been able to effectively curtail transmission of HIV to the infant during or after pregnancy, resulting in about 90% of the estimated 420,000 newly infected children per annum occurring in Sub-Saharan Africa. *Department of Obstetrics and Gynaecology †Reproductive Health and HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa Correspondence: Franco Guidozzi, MBBCh, FRCOG, FCOG, Department of Obstetrics and Gynaecology, Area 174, Block 1, Private bag X39, Johannesburg Hospital, Johannesburg, South Africa 2000. E-mail: Franco.Guidozzi@wits.ac.za © 2009 Lippincott Williams & Wilkins, Inc.