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Medication Abortion

BARTZ, DEBORAH MD, MPH; GOLDBERG, ALISA MD, MPH

Clinical Obstetrics & Gynecology: June 2009 - Volume 52 - Issue 2 - pp 140-150
doi: 10.1097/GRF.0b013e3181a2b026
Pregnancy Termination

Medical methods for pregnancy termination in early gestation offer women an alternative to surgical evacuation and have the potential to improve access globally to safe abortion. Several drug regimens are used with varying efficacy including mifepristone plus misoprostol, misoprostol alone, and methotrexate plus misoprostol. Where available, a mifepristone plus misoprostol regimen is most frequently used and is highly effective for early abortion. We review these drug regimens along with clinical practice recommendations including patient counseling and selection, regimen administration location, expected side effects, and follow-up procedures. Overall, women who choose medical abortion report high levels of satisfaction.

Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Brigham and Women's Hospital, Planned Parenthood League of Massachusetts, Boston, Massachusetts

Funding Disclosures: None.

Correspondence: Deborah Bartz, MD, MPH, Department of Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School, Brigham and Women's Hospital, Planned Parenthood League of Massachusetts, Boston, MA. E-mail: dbartz@partners.org

© 2009 Lippincott Williams & Wilkins, Inc.