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Imaging for Diagnosis and Treatment of Cerebral Palsy

SHIMONY, JOSHUA S. MD, PhD*; LAWRENCE, RUSSELL MD; NEIL, JEFFREY J. MD, PhD* †; INDER, TERRIE E. MD, PhD* †

Clinical Obstetrics & Gynecology: December 2008 - Volume 51 - Issue 4 - pp 787-799
doi: 10.1097/GRF.0b013e3181870b22
Diagnosis, Prevention, and Treatment of Cerebral Palsy

Neuroimaging, particularly with magnetic resonance techniques, can provide insight into the pattern and severity of cerebral injury underlying cerebral palsy providing a neuroanatomic understanding of the motor and related deficits. Early identification of injury before the establishment of marked motor deficits provides an opportunity for neuroprotection. Neuroimaging provides a robust manner for early delineation of the risk and nature of cerebral palsy that an infant may face. In the future, imaging may provide more functional methods, including novel methods such as optical tomography, map regeneration, adaptation, and functional recovery.

*Mallinckrodt Institute of Radiology

Departments of Pediatrics and Neurology, Washington University School of Medicine, St. Louis, Missouri

Correspondence: Terrie E. Inder, MD, PhD, Departments of Pediatrics, Neurology, and Radiology, St. Louis Children's Hospital, One Children's Place, St Louis, MO 63110. E-mail: spongc@dir49.nichd.nih.gov

Supported in part by NIH K23 HD053212 (J.S.S.), NIH R01 HD057098 (T.E.I., J.J.N.), NIH R01 HD058056 (T.E.I.), and NIH R01 NS037357 (J.J.N.).

© 2008 Lippincott Williams & Wilkins, Inc.