Hormone Therapy and StrokeBIRGE, STANLEY J. MDClinical Obstetrics & Gynecology: September 2008 - Volume 51 - Issue 3 - pp 581-591 doi: 10.1097/GRF.0b013e318181df30 Evidence-Based Approach to Menopause Abstract Author Information Available biochemical and clinical data are sufficiently compelling to recommend low dose or transdermal hormone therapy for the management of menopausal symptoms when possible. Women initiating low dose or transdermal hormone therapy are not at increased risk of cardiovascular disease, stroke, venous thrombotic disease, and breast cancer. Evidence suggests that these outcomes are favorably affected by low-dose hormone therapy and persist with continuation of therapy. Division of Geriatrics and Nutritional Science, Washington University School of Medicine, St Louis, Missouri Correspondence: Stanley J. Birge, MD, Division of Geriatrics and Nutritional Science, Washington University School of Medicine, 4488 Forest Park Blvd, St Louis, MO 63108. E-mail: SBirge@DOM.wustl.edu © 2008 Lippincott Williams & Wilkins, Inc.