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The Use of Prenatal Ultrasound for the Detection of Fetal Aneuploidy

HOLMGREN, CALLA MD*; LACOURSIERE, DAPHNE YVETTE MD, MPH

Clinical Obstetrics & Gynecology: March 2008 - Volume 51 - Issue 1 - pp 48-61
doi: 10.1097/GRF.0b013e31816163e3
Current Concepts in Prenatal Genetics

Ultrasound is a noninvasive tool for early evaluation of the fetus and intrauterine environment. Its limitations include the lack of standardization of evaluation that patients receive, as well as varying sonologist's experience and equipment. Further, many fetuses with aneuploidy will not demonstrate significant sonographic findings, making detection limited. With regard to aneuploidy screening, its utility is improved when used in conjunction with analyte screening. Early recognition of fetal compromise allows families time for preparation and informed management of the gestation.

*Divison of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Washington, Seattle, Washington

Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah

Correspondence: Calla Holmgren, MD, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Washington, PO Box 356460, Seattle, WA. E-mail: cholmgren73@yahoo.com

© 2008 Lippincott Williams & Wilkins, Inc.