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Antiphospholipid Syndrome and Thrombosis

WARE BRANCH, D. MD; Eller, ALEXANDRA GROSVENOR MD

Clinical Obstetrics & Gynecology: December 2006 - Volume 49 - Issue 4 - pp 861-874
doi: 10.1097/01.grf.0000211955.61121.3b
Thrombotic Disorders

The antiphospholipid syndrome is an autoimmune condition in which venous or arterial thrombosis is a primary clinical feature. The other primary clinical feature is adverse pregnancy outcome, specifically recurrent miscarriage, fetal death, or preterm delivery due to severe preeclampsia or placental insufficiency. The diagnostic autoantibodies for antiphospholipid syndrome are lupus anticoagulant, anticardiolipin, or anti-β2-glycoprotein I.

University of Utah Health Sciences Center and Intermountain Healthcare, Salt Lake City, Utah

Correspondence: D. Ware Branch, MD, University of Utah School of Medicine, 30 North 1900 East, Room 2B200 SOM, Salt Lake City, UT 84132. E-mail: ware.branch@hsc.utah.edu

© 2006 Lippincott Williams & Wilkins, Inc.