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Oxytocin for Induction of Labor

SMITH, JENNIFER G. MD, PhD; MERRILL, DAVID C. MD, PhD

Clinical Obstetrics and Gynecology: September 2006 - Volume 49 - Issue 3 - p 594-608
Original Articles

Oxytocin is the most common pharmacologic agent used for the induction and augmentation of labor. Oxytocin protocols can be divided into high-dose and low-dose protocols depending on the initial dose and the amount and rate of sequential increase in dose. Despite the frequency with which oxytocin in used in clinical practice, there is little consensus regarding which protocol is most appropriate. The purpose of this chapter is to review the most current data concerning recommendations for the use of oxytocin in the induction of labor, including cases of intrauterine fetal demise and vaginal birth after cesarean.

Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston-Salem, North Carolina

Correspondence: David C. Merrill, MD, PhD, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157. E-mail: dmerrill@wfubmc.edu

Copyright © 2006 Wolters Kluwer Health, Inc. All rights reserved.