Purpose: To describe the novel finding of epileptic spasms arising from a cingulate lesion.
Methods: We describe two children presenting with epileptic spasms who had lesions of the cingulate gyrus on MRI.
Results: In both patients, the lesions involved the midcingulate cortex. Seizures were characterized by prominent motor manifestations and resembled spasms. Both patients had a complete resolution of seizures after resection of their cingulate lesions.
Discussion: Cingulate seizures can present with a variety of behaviors including complex motor manifestations, vocalizations, and autonomic changes. Lesions in the midcingulate cortex can also produce epileptic spasms.
From the *Division of Pediatric Neurology, Department of Pediatrics, †Division of Neurosurgery, Department of Surgery, University of British Columbia and British Columbia’s Children’s Hospital, Vancouver, British Columbia, Canada.
The authors have no conflict of interest to disclose.
Address correspondence and reprint requests to Dr. Mary B. Connolly, Division of Neurology, Department of Pediatrics, BC Children’s Hospital, 4480 Oak Street, Vancouver BC, Canada V6H 3V4; e-mail: firstname.lastname@example.org.