Methylphenidate-Induced Psychosis in Adult Attention-Deficit/Hyperactivity Disorder: Report of 3 New Cases and Review of the LiteratureKraemer, Markus MD*†; Uekermann, Jennifer PhD*; Wiltfang, Jens MD*; Kis, Bernhard MD*Clinical Neuropharmacology: July 2010 - Volume 33 - Issue 4 - pp 204-206 doi: 10.1097/WNF.0b013e3181e29174 Review Articles Abstract Author Information Objective: We present 3 new cases of psychotic symptoms in patients with adult attention-deficit/hyperactivity disorder while regularly treated with a stimulant therapy with methylphenidate. Methods: Existing literature about this theme is reviewed, and potential mechanisms are discussed. Results and Conclusions: Medication with methylphenidate should be avoided in patients with vulnerability to schizophrenia and in drug addiction, but reported cases without these risk factors demonstrate that a careful and regular psychiatric monitoring is essential in all patients treated with methylphenidate. *Outpatient Clinic for Adult ADHD, Department of Psychiatry and Psychotherapy, University of Duisburg-Essen, LVR Clinic Essen; and †Department of Neurology, Alfried Krupp Hospital Essen, Essen, Germany. Address correspondence and reprint requests to Markus Kraemer, MD, Department of Neurology, Alfried Krupp Hospital, Alfried-Krupp-Strasse 21, 45117 Essen, Germany; E-mail: email@example.com There was no funding. © 2010 Lippincott Williams & Wilkins, Inc.