Rapid Weight Gain Associated With Edema After Use of Paroxetine and Venlafaxine: 2 Case Reports.Uguz, Faruk MDClinical Neuropharmacology: Post Author Corrections: January 17, 2014 doi: 10.1097/WNF.0000000000000012 Case Report: PDF Only Abstract Edema is a rarely observed adverse effect of the usage of antidepressant, with only few case reports of peripheral edema in the literature. This report included 2 patients who presented with rapid weight gain related to edema after the use of venlafaxine and paroxetine alone. The adverse effects developed within 2 to 3 weeks after the start of the treatments and completely resolved after their discontinuation. Copyright (C) 2017 Wolters Kluwer Health, Inc. All rights reserved.