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Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0000000000000044
Article

Effect of Religious Fasting on Tear Osmolarity and Ocular Surface

Koktekir, Bengu Ekinci M.D.; Bozkurt, Banu M.D.; Gonul, Saban M.D.; Gedik, Sansal M.D.; Okudan, Suleyman M.D.

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Abstract

Objective:

To evaluate the effects of religious fasting on tear secretion, tear osmolarity, corneal topography, and ocular aberrations.

Methods:

This prospective controlled study comprised 29 eyes of 29 healthy men. Before ophthalmologic examination, all subjects underwent corneal topography by a placido disc corneal topography and aberrometry device (OPD Scan II). Tear osmolarity was measured using OcuSense TearLab osmometer. Ocular surface disease index (OSDI) scores, tear break-up time (BUT), Schirmer I test, and lissamine green staining were evaluated. The measurements taken before and during Ramadan at the same hours between 4.00 and 5.00 pm were compared using paired sample t test, and a P value less than 0.05 was accepted as statistically significant.

Results:

The mean age of the study group was 27.8±5.9 years (range, 20–47 years). The mean tear osmolarity values were measured as 285.6±8.2 mOsm/L and 293.3±16.0 mOsm/L, whereas the mean Schirmer I values were 14.8±6.0 mm and 10.6±5.3 mm in nonfasting and fasting periods, respectively. Tear osmolarity, OSDI, and Oxford grading scores significantly increased (P=0.02, P=0.002, P=0.003, respectively), whereas Schirmer I values and intraocular pressure decreased (both, P<0.001) during the fasting period compared with the nonfasting period. There were no significant differences in tear BUT, keratometry values, and corneal aberration measurements between nonfasting and fasting periods (P>0.05, for all).

Conclusion:

Fasting significantly decreases tear production and increases tear osmolarity; however, it does not deteriorate corneal topographic parameters and ocular aberrations in healthy subjects.

© 2014 Contact Lens Association of Ophthalmologists

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