Eye & Contact Lens

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Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0000000000000018

Systane® Ultra Lubricant Eye Drops for Treatment of Contact Lens–Related Dryness

McDonald, Marguerite M.D.; Schachet, John L. O.D.; Lievens, Christopher W. O.D., M.S.; Kern, Jami R. M.B.A., Ph.D.

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Objectives: To assess the clinical performance of Systane® Ultra lubricant eye drops in daily disposable soft contact lens wearers who experience contact lens–related dryness.

Methods: In this randomized, investigator-masked study, daily disposable lens wearers with symptoms of dryness were randomized to use Systane Ultra lubricant eye drops or to no treatment. The lubricant regimen was applied twice a day, 10 minutes before lens insertion and after lens removal, for the 2-week study period. Subjective comfort, wear time, and visual acuity were assessed at baseline and after 2 weeks.

Results: A total of 89 daily disposable lens wearers were randomly assigned to the Systane Ultra group (n=44) or the control group (n=45). Two weeks of Systane Ultra lubricant eye drop use resulted in a significant increase in comfortable lens wear time when compared with baseline assessment (P=0.001) and a trend toward significant improvement compared with the control group (P=0.078). End-of-the-day comfort was significantly improved in the Systane Ultra group compared with the control group (P=0.007). A significant reduction in the overall dryness (P<0.001) and end-of-day dryness (P=0.047) was observed in subjects using the Systane Ultra lubricant eye drops compared with the control group.

Conclusion: The study demonstrates that Systane Ultra lubricant eye drops applied before and after contact lens wear is an effective artificial tear for alleviating symptoms of contact lens–related dry eye.

© 2014 Contact Lens Association of Ophthalmologists, Inc.


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