Eye & Contact Lens

Skip Navigation LinksHome > July 2013 - Volume 39 - Issue 4 > Management of Bullous Keratopathy-Related Ulcer With Autolog...
Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0b013e31825f6386
Case Report

Management of Bullous Keratopathy-Related Ulcer With Autologous Serum

Mataftsi, Asimina M.D., Ph.D., M.R.C.Ophth.; Bourtoulamaiou, Areti M.D.; Anastasilakis, Konstantinos M.D.; Ziakas, Nikolaos G. M.D., Ph.D.; Dimitrakos, Stavros A. M.D., Ph.D.

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Purpose: The aim of this study was to report the use of autologous serum eyedrops (ASEs) for resolution of a corneal ulcer secondary to bullous keratopathy.

Methods: This is a case report.

Results: A 66-year-old patient presented with an infected ulcer and hypopyon while using a bandage contact lens for bullous keratopathy. Staphylococcus warneri infection was treated with systemic and topical antibiotics, and ASEs were subsequently administered to enhance reepithelialization and to avoid the need for a bandage contact lens. The ASE treatment led to closure of the epithelium layer within 3 weeks, and it was subsequently tapered over the next 3 months. The clinical picture remained stable subjectively and objectively during the 7 months of follow-up.

Discussion: To the best of our knowledge, this is the first report of successful use of ASEs in treating and preventing recurrence of ulcers in the context of bullous keratopathy.

© 2013 Contact Lens Association of Ophthalmologists, Inc.


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