Eye & Contact Lens

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Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0b013e31826586c3

The Clinical Performance of Lenses Disposed of Daily Can Vary Considerably

Diec, Jennie B.Optom.; Lazon de la Jara, Percy Ph.D.; Willcox, Mark Ph.D.; Holden, Brien A. Ph.D.

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Objectives: To evaluate clinical performance of three lens types disposed of on a daily disposable (DD) basis.

Method: A total of 120 participants were randomized into one of three lens types (etafilcon A, narafilcon A, and senofilcon A), all worn bilaterally on a DD regime. Participants were observed at baseline, 2-week, and 1- and 3-month visits where ocular physiology and lens performance variables were collected on a 0 to 4 grading scale in 0.1 increments. Subjective comfort and vision ratings were collected on a 1 to 100 rating scale and in the form of symptom severity.

Results: Forty participants wore each lens type with no differences in age or gender between groups (P>0.05). Etafilcon A exhibited more limbal redness compared with either of the other lens types (P<0.01). More superior corneal staining was noted with narafilcon A lenses compared with senofilcon A (P<0.01), and more superior conjunctival indentation was noted for narafilcon A compared with etafilcon A (P=0.001). No differences were found between lenses in the 1 to 100 rating scale (P>0.05). Narafilcon A showed more moderate to severe dryness symptoms and symptoms of blurred vision at lens wearing visits (P<0.05). One bilateral contact lens papillary conjunctivitis, one unilateral superior epithelial arcuate lesion, and one infiltrative keratitis were associated with narafilcon A only. Of the seven discontinuations, six were from the narafilcon A group.

Conclusion: Different contact lens materials and designs, worn on the same DD modality, elicit different ocular and patient responses. Narafilcon A did not perform clinically as well as etafilcon A and senofilcon A worn on a DD modality.

© 2012 Lippincott Williams & Wilkins, Inc.


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