You could be reading the full-text of this article now if you...

If you have access to this article through your institution,
you can view this article in

Effect of Multizone Refractive Multifocal Contact Lenses on Standard Automated Perimetry

Madrid-Costa, David Ph.D.; Ruiz-Alcocer, Javier O.D., M.Sc.; García-Lázaro, Santiago Ph.D.; Albarrán-Diego, César O.D., M.Sc.; Ferrer-Blasco, Teresa Ph.D.

Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0b013e31825fed3b

Purpose: The aim of this study was to evaluate whether the creation of 2 foci (distance and near) provided by multizone refractive multifocal contact lenses (CLs) for presbyopia correction affects the measurements on Humphreys 24-2 Swedish interactive threshold algorithm (SITA) standard automated perimetry (SAP).

Methods: In this crossover study, 30 subjects were fitted in random order with either a multifocal CL or a monofocal CL. After 1 month, a Humphrey 24-2 SITA standard strategy was performed. The visual field global indices (the mean deviation [MD] and pattern standard deviation [PSD]), reliability indices, test duration, and number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% on pattern deviation probability plots were determined and compared between multifocal and monofocal CLs.

Results: Thirty eyes of 30 subjects were included in this study. There were no statistically significant differences in reliability indices or test duration. There was a statistically significant reduction in the MD with the multifocal CL compared with monfocal CL (P=0.001). Differences were not found in PSD nor in the number of depressed points deviating at P<5%, P<2%, P<1%, and P<0.5% in the pattern deviation probability maps studied.

Conclusions: The results of this study suggest that the multizone refractive lens produces a generalized depression in threshold sensitivity as measured by the Humphreys 24-2 SITA SAP.

Author Information

Optometry Research Group (D.M.-C., J.R.-A., S.G.-L., C.A.-D., T.F.-B.), Optics Department, University of Valencia, Valencia, Spain.

Address correspondence and reprint requests to David Madrid-Costa, Ph.D., Optometry Research Group, Optics Department, University of Valencia, Spain; e-mail:

Supported in part by a Ministerio de Ciencia e Innovación Research Grants (#SAF2008-01114# and #SAF2009-13342#) and a scholarship Jose Castillejo to Robert Montés-Micó.

The authors have no proprietary interest in any of the materials mentioned in this article.

Accepted May 16, 2012

© 2012 Lippincott Williams & Wilkins, Inc.