Eye & Contact Lens

Skip Navigation LinksHome > September 2012 - Volume 38 - Issue 5 > Corneal Melanoma: Report of Three Cases
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Eye & Contact Lens: Science & Clinical Practice:
doi: 10.1097/ICL.0b013e318237d195
Case Report

Corneal Melanoma: Report of Three Cases

Uçakhan-Gündüz, Ömür M.D.; Gündüz, Kaan M.D.; Karslioğlu, Melisa Z. M.D.; Okçu-Heper, Aylin M.D.; Kanpolat, Ayfer M.D.

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Objectives: We report three cases of corneal melanoma: two without conjunctival primary acquired melanosis or melanoma and one with a history of conjunctival melanoma.

Methods: Report of 3 cases with corneal melanoma and literature review.

Results: Medical records of three patients with the diagnosis of corneal melanoma were reviewed. Total excisional biopsy with corneal epitheliectomy using 20% ethanol was performed. Postoperative topical chemotherapy with 0.04% mitomycin-C was used for 4 weeks as adjunctive therapy. The follow-up ranged from 13 months to 7 years. Each of the two patients experienced two recurrences. One was treated in a fashion similar to that of the initial tumor, and the other was treated by enucleation. None of the patients developed regional or distant metastasis.

Conclusions: Malignant melanoma can rarely occur on the cornea with no contiguous conjunctival component. Eye-conserving treatment should be attempted first. Recurrences may occur, and a close follow-up is necessary.

© 2012 Lippincott Williams & Wilkins, Inc.


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