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Critical Care Medicine:
doi: 10.1097/CCM.0b013e31828ce07c
Concise Definitive Review

The Use of Neuromuscular Blocking Agents in the ICU: Where Are We Now?

Greenberg, Steven B. MD1,2; Vender, Jeffery MD, MBA, FCCP, FCCM1,2

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Abstract

Intensivists use neuromuscular blocking agents for a variety of clinical conditions, including for emergency intubation, acute respiratory distress syndrome, status asthmaticus, elevated intracranial pressure, elevated intra-abdominal pressure, and therapeutic hypothermia after ventricular fibrillation–associated cardiac arrest. The continued creation and use of evidence-based guidelines and protocols could ensure that neuromuscular blocking agents are used and monitored appropriately. A collaborative multidisciplinary approach coupled with constant review of the pharmacology, dosing, drug interactions, and monitoring techniques may reduce the adverse events associated with the use of neuromuscular blocking agents.

© 2013 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins

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