Critical Care Medicine

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Critical Care Medicine:
doi: 10.1097/CCM.0b013e31821cb246
Concise Definitive Review

Necrotizing soft-tissue infections

Ustin, Jeffrey S. MS, MD; Malangoni, Mark A. MD, FACS

Section Editor(s): Sevransky, Jonathan E. MD, MHS



In the article on page 2156 of the September issue, in Table 1, the adult intravenous dose for doxycycline is listed as 1 gm q12h. The correct dose is 100 mg q12h.

Critical Care Medicine. 39(11):2592, November 2011.

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Objective: To provide a contemporary review of the diagnosis and management of necrotizing soft-tissue infections.

Data Sources: Scientific literature and internet sources.

Study Selection: Major articles of importance in this area.

Conclusions: The mortality for necrotizing soft-tissue infections appears to be decreasing, possibly due to improved recognition and earlier delivery of more effective therapy. Establishing a diagnosis and initiating treatment as soon as possible provides the best opportunity for a good outcome.

© 2011 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins

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