Skip Navigation LinksHome > September/October 2004 - Volume 12 - Issue 5 > Coronary Artery Rupture Associated With Amphetamine Abuse
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Cardiology in Review:
Finalist, Fellowship/Residency Clinical Case Contest

Coronary Artery Rupture Associated With Amphetamine Abuse

Brennan, Kathleen MD; Shurmur, Scott MD; Elhendy, Abdou MD, PhD

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Abstract

We report a case of spontaneous coronary artery rupture associated with amphetamine abuse in a 31-year-old woman. The patient presented to the emergency department with sudden onset of central chest pain and a normal electrocardiogram. Cardiac enzymes were consistent with acute myocardial infarction. Drug screening was positive for amphetamines. Coronary angiography revealed an aneurysmal lesion with 99% occlusion of the proximal left circumflex coronary artery and extravasation of contrast material. Percutaneous coronary intervention was performed with stent placement. Antegrade flow was achieved without residual stenosis. This is the first reported case of coronary artery rupture related to amphetamine abuse.

© 2004 Lippincott Williams & Wilkins, Inc.

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