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Enteral Nutrition Intolerance in Critically Ill Septic Burn Patients

Lavrentieva, Athina MD*; Kontakiotis, Theodore MD; Bitzani, Militsa MD*

doi: 10.1097/BCR.0b013e3182a22403
Original Articles

The purpose of this study was to investigate the frequency of enteral feeding intolerance in critically ill septic burn patients, the effect of enteral feeding intolerance on the efficacy of feeding, the correlation between the infection marker (procalcitonin [PCT]) and the nutrition status marker (prealbumin) and the impact of feeding intolerance on the outcome of septic burn patients. From January 2009 to December 2012 the data of all burn patients with the diagnosis of sepsis who were placed on enteral nutrition were analyzed. Septic patients were divided into two groups: group A, septic patients who developed feeding intolerance; group B, septic patients who did not develop feeding intolerance. Demographic and clinical characteristics of patients were analyzed and compared. The diagnosis of sepsis was applied to 29% of all patients. Of these patients 35% developed intolerance to enteral feeding throughout the septic period. A statistically significant increase in mean PCT level and a decrease in prealbumin level was observed during the sepsis period. Group A patients had statistically significant lower mean caloric intake, higher PCT:prealbumin ratio, higher pneumonia incidence, higher Sequential Organ Failure Assessment Maximum Score, a longer duration of mechanical ventilation, and a higher mortality rate in comparison with the septic patients without gastric feeding intolerance. The authors concluded that a high percentage of septic burn patients developed enteral feeding intolerance. Enteral feeding intolerance seems to have a negative impact on the patients’ nutritional status, morbidity, and mortality.

From the *Burn Intensive Care Unit, Papanikolaou General Hospital, Thessaloniki, Greece; and Pulmonary Department, Aristotle University Thessaloniki, Papanikolaou General Hospital, Greece.

Address correspondence to Athina Lavrentieva, MD, Papanikolaou General Hospital, Hadzipanagiotidi 2, Thessaloniki 55236, Greece.

© 2014 The American Burn Association