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Inflammation and the Host Response to Injury: An Overview of the Multicenter Study of the Genomic and Proteomic Response to Burn Injury

Klein, Matthew B. MD*; Silver, Geoff MD†; Gamelli, Richard L. MD†; Gibran, Nicole S. MD*; Herndon, David N. MD‡; Hunt, John L. MD§; Tompkins, Ronald G. MD¶; the Inflammation and the Host Response to Injury Investigators

doi: 10.1097/01.BCR.0000227477.33877.E6
Original Articles

Inflammation and the Host Response to Injury is a prospective, multicenter, federally funded collaborative study of the genomic and proteomic basis for injury response. This study has brought together clinical specialists in burn injury with experts in genomics, proteomics, and bioinformatics to answer questions related to immunoinflammatory responses to injury. The purpose of this report is to describe the structure, organization, goals, and current progress of this Glue Grant project.

From the *University of Washington Burn Center, Harborview Medical Center, Seattle, Washington; †Loyola University Medical Center, Maywood, Illinois; ‡Parkland Memorial Hospital, University of Texas Southwestern, Dallas, Texas; §University of Texas Medical Branch and Shriners Hospital, Galveston, Texas; and ¶Massachusetts General Hospital and Shriners Hospital, Boston, Massachusetts.

© 2006 The American Burn Association