The Safety of Cryobiopsy in Diagnosing Carcinoid Tumors

Boyd, Michael MD; Sahebazamani, Mitra MD; Ie, Susanti MD; Rubio, Edmundo MD

Journal of Bronchology & Interventional Pulmonology: July 2014 - Volume 21 - Issue 3 - p 234–236
doi: 10.1097/LBR.0000000000000079
Case Reports

Background: Cryotherapy probes have recently found an expanding role as a routine diagnostic instrument to sample endobronchial pathology. However, its overall safety and efficacy in biopsying carcinoid tumors has not been clearly established. Carcinoid tumors are more vascular and may be prone to more bleeding when biopsied by a cryoprobe.

Methods: Review of 5 cases that underwent cryoprobe biopsies for carcinoid tumors was carried out.

Results: Cryobiopsy was successful to diagnose all suspected cases of endobronchial carcinoid tumors. The samples obtained were of good quality and devoid of crush artifact. There was no associated significant bleeding or other complications.

Conclusions: Cryotherapy probe biopsy should be considered a safe and effective approach to diagnose carcinoid tumors.

Section of Pulmonary, Critical Care, Environmental, and Sleep Medicine, Carilion Clinic, Virginia Tech Carilion School of Medicine, Roanoke, VA

Disclosure: There is no conflict of interest or other disclosures.

Reprints: Michael Boyd, MD, Section of Pulmonary, Critical Care, Environmental, and Sleep Medicine, Carilion Clinic, Virginia Tech Carilion School of Medicine, 1906 Belleview Ave, Roanoke, VA 24014 (e-mail: mbboyd@carilionclinic.org).

Received July 5, 2013

Accepted April 22, 2014

© 2014 by Lippincott Williams & Wilkins.