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Advances in Skin & Wound Care:
doi: 10.1097/01.ASW.0000443270.71030.71
Supplement

Case Series of Lower-Extremity Chronic Wounds Managed with an Antibacterial Foam Dressing Bound with Gentian Violet and Methylene Blue

Coutts, Patricia M. RN, IIWCC (Toronto); Ryan, Judy RN, IIWCC (Toronto); Sibbald, R. Gary BSc, MD, MEd, FRCPC(Med Derm), MACP, FAAD, MAPWCA

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Abstract

OBJECTIVE: To evaluate an antibacterial dressing for the management of lower-extremity chronic wounds with critical colonization.

DESIGN: A case series of n = 15 patients with lower-extremity chronic wounds were treated with an antibacterial foam dressing consisting of polyvinyl alcohol (PVA) foam bound with gentian violet and methylene blue (Hydrofera Blue; Hydrofera, LLC, Willimantic, Connecticut).

SETTING: An outpatient clinic in Ontario, Canada.

PATIENTS: The dressing was applied to diabetic foot ulcers (n = 8) and other venous/leg wound etiologies (n = 7). The study population was clinically challenging due to high mean body weight, extended wound durations, and high diabetes prevalence.

MAIN OUTCOME MEASURES: Wounds were assessed for clinical signs of superficial and deep/surrounding bacterial burden using the validated NERDS and STONEES mnemonic and with semiquantitative bacterial swabs. Changes in wound size, pain, and other clinical parameters were also recorded.

MAIN RESULTS: Improvements in surface critical colonization and pain score at the end of the study period were noted in some patients, especially in patients with diabetic foot ulcers. A decreasing wound size was observed in 8 of the 14 patients (57%) at week 4. One patient was excluded from wound size change analysis.

CONCLUSIONS: An antibacterial foam dressing consisting of PVA foam bound with gentian violet and methylene blue showed encouraging results in a clinically challenging study population. This dressing may be a suitable option for lower-extremity chronic wounds demonstrating an increased superficial bacterial burden. Further investigation focused on identifying the characteristics of patients who are most responsive to the dressing is warranted.

© 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins. All world rights reserved.

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