Skip Navigation LinksHome > October 2013 - Volume 26 - Issue 10 > Urinary Bladder Matrix for the Treatment of Recalcitrant Non...
Advances in Skin & Wound Care:
doi: 10.1097/01.ASW.0000434617.57451.e6
Departments: Case Report

Urinary Bladder Matrix for the Treatment of Recalcitrant Nonhealing Radiation Wounds

Rommer, Elizabeth A. BS; Peric, Mirna BA; Wong, Alex MD, FACS

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Abstract

Chronic wounds in previously radiated tissue are challenging to treat. In this article, the authors describe 3 such wounds that failed to heal despite multiple treatments with traditional wound healing methods. Treatment with porcine urinary bladder matrix, an extracellular matrix material, was initiated to facilitate epithelialization and promote wound healing. MatriStem powder (ACell, Inc, Columbia, Maryland), MatriStem (ACell, Inc) sheet, and DuoDerm (ConvaTec, Skillman, New Jersey) were applied biweekly and resulted in complete wound closure within 3 weeks of initial application for all 3 cases. All wounds remained closed 9 months following treatment, suggesting a role for urinary bladder matrix in the management of chronic wounds in the setting of irradiated tissue.

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

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