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Advances in Skin & Wound Care:
doi: 10.1097/01.ASW.0000426714.57540.c4
Features: Original Investigations

Observations of Periwound Skin Protection in Venous Ulcers: A Comparison of Treatments

Hunter, Susan M. MSN, RN; Langemo, Diane PhD, RN, FAAN; Thompson, Patricia MS, RN; Hanson, Darlene MS, RN; Anderson, Julie PhD, RN; Oh, In Eui BSN, RN; Paulson, Rolf MD, FACP; Rustvang, Dan CWS, FNP; Dorman, Seth CWS, FNP; Roth, David L. PhD

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OBJECTIVE: The objective of this study was to examine the effectiveness of 2 products on venous ulcer periwound skin.

DESIGN: This was a descriptive comparative study.

SETTING: An outpatient wound care clinic in a rural Midwestern area of the United States.

PARTICIPANTS: Participants included a retrospective group of 50 patients and a prospective group of 28 patients.

INTERVENTION: The intervention compared the experimental product (Remedy Nutrashield; Medline Industries, Mundelein, Illinois) versus Cavilon Moisturizing Lotion (3M, St Paul, Minnesota).

OUTCOME MEASURES: The mean outcome measures were a decrease in periwound and ulcer size.

MAIN RESULTS: For the periwound size, the estimated rates of change were as follows: 0.092 (SE, 0.021) cm/d and −0.026 (SE, 0.014) cm/d for products B and A groups, respectively. The decrease for the experimental group was significantly greater than the attenuated decrease for the retrospective cases (t297 = −2.57, P = .01), and the decrease for product B group was also significantly different from zero (t76 = −4.34, P < .0001). For the ulcer size model, the estimated rates of change were −0.272 (SE, 0.102) cm2/d and −0.130 (SE, 0.067) cm2/d for the experimental and retrospective groups, respectively. The rate for the experimental group was significantly less than zero (t76 = −2.67, P = .009), but there was no significant difference between prospective and retrospective cases in the rates of reduction in ulcer size (t308 = −1.16, P = .25).

CONCLUSION: The results of this study illustrate how the integrity of the periwound skin may be an important determinant in decreasing periwound and ulcer size.

© 2013 Lippincott Williams & Wilkins, Inc.


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