Institutional members access full text with Ovid®

Role of a Point-of-Care Protease Activity Diagnostic Test in Canadian Clinical Practice: A Canadian Expert Consensus©

Sibbald, R. Gary BSc, MD, MEd, FRCPC(Med Derm), MACP, FAAD, MAPWCA, panel co-chairperson; Snyder, Robert J. DPM, MSc, CWS; Botros, Mariam DCh, IIWCC; Burrows, Cathy RN, BScN, MScCH; Coutts, Patricia RN; D’Souza, Lincoln RN; Kuhnke, Janet ET PhD(c), MS, BSN, RN; Labrecque, Chantal MSN, BSN, RN; Laforet, Karen RN, MClSc-WH, IIWCC; Landis, Stephan MD, FRCP(C); LeBlanc, Kimberly MN, RN, CETN(C), IIWCC; Maida, Vincent MD,MSc, BSc, CCFP, FCFP, ABHPM; Pearson, Christine RN; Suitor, Michele RN, MN, NP; Belley, Richard MD, CFPC; Mehta, Sowmil MD, BEng, FRCSC

Advances in Skin & Wound Care: June 2012 - Volume 25 - Issue 6 - p 267–275
doi: 10.1097/01.ASW.0000415344.22307.ba
Features: Original Investigations

ABSTRACT: Nonhealing wounds (stalled, healable) challenge affected individuals, wound clinicians, and society. Nonhealing may result despite local factors being corrected. The interplay between tissue degradation, increased inflammatory response, and abundant protease activity is a challenging quandary. A modified Delphi process was utilized to investigate a protease activity test and practice implications.

R. Gary Sibbald, BSc, MD, MEd, FRCPC(Med Derm), MACP, FAAD, MAPWCA, is Professor, Public Health and Medicine, University of Toronto, Ontario, Canada.

Robert J. Snyder, DPM, MSc, CWS, is Professor and Director of Clinical Research, Barry University SPM Miami Shores, Florida.

Mariam Botros, DCh, IIWCC, is Chiropodist and Clinical Coordinator, Wound Healing Clinic, Women’s College Hospital, Toronto, Ontario, Canada.

Cathy Burrows, RN, BScN, MScCH, (Wound Prevention and Care), is Staff Nurse, Queen Elizabeth II Hospital, Halifax Infirmary, Nova Scotia, Canada.

Patricia Coutts, RN, is President, Canadian Association of Wound Care, and Wound Care and Clinical Trial Coordinator, Toronto Regional Wound Clinic, Mississauga, Ontario, Canada.

Lincoln D’Souza, RN, is Senior Advisor/Manager, Wound and Stoma Program, McGill University Royal Victoria Hospital, Montreal, Quebec, Canada.

Janet Kuhnke, ET PhD(c), MS, BSN, RN, Instructor, Faculty, St. Lawrence College/Laurentian University, Cornwall, Ontario, Canada, and Queens’ University, Kingston, Ontario, Canada.

Chantal Labrecque, MSN, BSN, RN, is Wound Care Consultant, CliniConseil Inc, Montreal, Quebec.

Karen Laforet, RN, MClSc-WH, IIWCC, is Director of Clinical Services, Calea, Mississauga, Ontario.

Stephan Landis, MD, FRCP(C), is an Infectious Diseases Internist, Department of Hospital Medicine and Ambulatory Wound Clinic, Guelph General Hospital, Guelph, Ontario, Canada, and Dermatology Day Care and Wound Clinic, Women’s College Hospital, Toronto, Ontario, Canada.

Kimberly LeBlanc, MN, RN, CETN(C), IIWCC, is Advanced Practice Nurse, Clinical Nurse Specialist, KDS Professional Consulting, Ottawa, Ontario, Canada.

Vincent Maida, MD, MSc, BSc, CCFP, FCFP, ABHPM, is Assistant Professor, University of Toronto, Ontario, and is Clinical Assistant Professor, McMaster University, Hamilton, Ontario, Canada.

Christine Pearson, RN, is Treasurer, Canadian Association of Wound Care, and Community Wound Clinician, Vancouver Coastal Health, North Vancouver, British Columbia, Canada.

Michele Suitor, RN, MN, NP, is a Complex Wound Management Consultant and Educator, Stony Plain, Alberta, Canada.

Richard Belley, MD, CFPC, is a Family Physician, Complex Wound Care Clinic of the CSSS Alphonse Desjardins (Centre Hospitalier Affilié Universitaire Hotel Dieu de Lévis), and Associate Professor, Faculty of Medicine, Laval University, Quebec, Canada.

Sowmil Mehta, MD, BEng, FRCSC, is a Vascular and Interventional Surgeon, Complex Wound Management, Hôtel-Dieu Grace Hospital, Windsor, Ontario, Canada.

The authors disclose that the consensus meeting was supported by an unrestricted educational grant from Systagenix.

Dr Sibbald has disclosed that he is/was a recipient of grant/research funding from BSN Medical, 3M, Mö lnlycke, Coloplast, Gaymar, Johnson & Johnson (Systagenix), and KCI; is/was a consultant/advisor to BSN Medical, 3M, Gaymar, Mö lnlycke, Coloplast, Gaymar, Johnson & Johnson (Systagenix), KCI, Covidien, and the Registered Nurses Association of Ontario; is/was a member of the speaker’s bureau for BSN Medical, 3M, Mö lnlycke, Coloplast, Gaymar, Johnson & Johnson (Systagenix), and KCI.

Dr Snyder has disclosed that he is/was a recipient of grant/research funding from Integra and CoDa; he was a recipient of grant/research funding from Healthpoint; is/was a consultant/advisor to Systagenix and KCI; and he was a member of the speaker’s bureau for Advanced BioHealing.

Ms Burrows has disclosed that she is/was a consultant/advisor to Systagenix.

Ms Coutts has disclosed that she was a recipient of grant/research funding from BSN Medical, 3M, and Systagenix; is/was a consultant/advisor to Systagenix; was a consultant/advisor to Covidien, BSN Medical, and Coloplast; is/was a member of the speaker’s bureau for Mö lnlycke; is a member of the speaker’s bureau for BSN Medical and Coloplast; and is/was a member of the speaker’s bureau for Systagenix.

Mr D’Souza has disclosed that he was a recipient of grant/research funding from Systagenix; was a consultant/advisor to KCI, Smith & Nephew, and Advanced BioHealing; and was a member of the speaker’s bureau for KCI and Covidien.

Ms Laforet has disclosed that she is/was a consultant/advisor to Hollister; was a consultant/advisor to Systagenix; is/was a member of the speaker’s bureau for 3M; was a member of the speaker’s bureau for Systagenix, KCI, and Coloplast; and is/was a stock shareholder of 3M.

Ms LeBlanc has disclosed that she is a member of the speaker’s bureau for Johnson & Johnson, 3M, Mö lnlycke, KCI, and Hollister; and was a member of the speaker’s bureau for ConvaTec.

Ms Pearson has disclosed that she is a consultant/advisor to Hollister; and was a consultant/advisor to Systagenix.

Ms Labrecque has disclosed that she is/was a consultant/advisor to Hollister; and was a member of the speaker’s bureau for Systagenix, Hollister, 3M, and Coloplast.

Dr Belley has disclosed that he was a consultant/advisor to Systagenix.

Dr Botros, Dr Kuhnke, Dr Landis, Dr Maida, Ms Suitor, and Dr Mehta have disclosed that they have no financial relationships related to this article.

Acknowledgments: The authors would like to thank Joanna Gorski of Prescriptum Health Care Communications, Inc for taking notes during the consensus meeting and drafting the manuscript for critical review and revision by the authors.

The views expressed are those of the authors and do not necessarily reflect those of Systagenix. Copyright 2011 Canadian Consensus Panel.

Contents of this article were previously published as a supplement to Wound Care Canada, November 2011.

Submitted September 23, 2011; accepted January 13, 2012.

© 2012 Lippincott Williams & Wilkins, Inc.