Institutional members access full text with Ovid®

Share this article on:

Brukhonenko’s Autojector: The First Apparatus for Cardiopulmonary Bypass and Extracorporeal Life Support

Glyantsev Sergey P.; Bogopolsky, Pavel M.; Tchantchaleishvili, Vakhtang
doi: 10.1097/MAT.0000000000000605
Project Bionics: Moment in History: PDF Only

Sergey Brukhonenko was a prominent Soviet physician-scientist who from 1922 to 1924 developed a methodology for perfusing a canine head and keeping it alive using the first extracorporeal life support device he created called “Autojector.” From 1926 to 1927, in collaboration with surgeon Nikolay Terebinsky, he performed a series of perfusion experiments of the entire canine body using a more advanced model of Autojector. Subsequently, Brukhonenko concluded the possibility of extending this methodology to heart surgery. Although Brukhonenko never applied his device in clinical practice, Terebinsky used the concept from 1929 to 1940 on open heart experiments. Although he never received sufficient acknowledgement for his pioneering work, it must be recognized that Brukhonenko, along with Terebinsky, laid the groundwork for developing cardiac surgery in the Soviet Union.

Submitted for consideration December 2016 ; accepted for publication in revised form April 2017.

Disclosure: The authors have no conflicts of interest to report.

Correspondence: Sergey P. Glyantsev, Bakulev Scientific Center for Cardiovascular Surgery, 135 Rublevskoye Shosse, Moscow 121552, Russia. Email:

Copyright © 2017 by the American Society for Artificial Internal Organs