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The Effects of Propofol and Isoflurane Sedation on the Outcomes of Surgical Patients Receiving Extracorporeal Membrane Oxygenation

Verkoyen, Kai; Schildhauer, Thomas A.; Strauch, Justus T.; Swol, Justyna

doi: 10.1097/MAT.0000000000000466
Clinical Critical Care

This article resurrects a historical technique using a new technology by describing the results of a retrospective, observational, single-center study that investigated the effects of propofol compared with isoflurane sedation on patient outcomes after extracorporeal membrane oxygenation (ECMO). No differences in patient outcomes were observed between the propofol and isoflurane groups. Nevertheless, the results of this study might improve our understanding of the effects of sedation on patient outcomes after ECMO and provide insight into the effects of spontaneous breathing during ECMO.

From the *Department of General and Trauma Surgery, BG University Hospital Bergmannsheil, Bochum, Germany; Department of Cardiac and Thoracic Surgery, BG University Hospital Bergmannsheil, Bochum, Germany; and Department of Intensive Care and Emergency Medicine, HELIOS Frankenwaldklinik Kronach, Kronach, Germany.

Submitted for consideration March 2016; accepted for publication in revised form August 2016.

Disclosures: The authors have no conflicts of interest to report.

Patients’ treatment has been performed at the Surgical ICU; BG University Hospital Bergmannsheil Ruhr-University Bochum, Department of General and Trauma Surgery.

Correspondence: Justyna Swol, Department of Intensive Care and Emergency Medicine, HELIOS Frankenwaldklinik Kronach, 96317 Kronach, Germany. Email: jswol@icloud.com.

Copyright © 2017 by the American Society for Artificial Internal Organs