Anti-Cancer Drugs

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Anti-Cancer Drugs:
January 2009 - Volume 20 - Issue 1 - pp 75-78
doi: 10.1097/CAD.0b013e328312659a
Case Reports

Alpha-fetoprotein expressing metastastic adenocarcinoma of the esophago-gastric junction responding favorably to capecitabine and oxaliplatin

Kripp, Melanie; Ströbel, Philipp; Dinter, Dietmar; Lukan, Nadine; Hochhaus, Andreas; Hofheinz, Ralf-Dieter

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Abstract

Alpha-fetoprotein-producing metastatic adenocarcinoma of the stomach or the esophago-gastric junction usually exhibits either no or only short-term remission while receiving palliative chemotherapy. We report on a 76-year-old male patient suffering from an unresectable α-fetoprotein-producing adenocarcinoma of the esophago-gastric junction with several liver metastases. He was treated with capecitabine and oxaliplatin-based combination therapy. A long-lasting major remission was observed resulting in a survival of 18.5 months.

© 2009 Lippincott Williams & Wilkins, Inc.

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