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Annals of Plastic Surgery:
doi: 10.1097/SAP.0000000000000032
Head and Neck Surgery

Recurrence of Infantile Hemangioma After Termination of Propranolol Treatment

Chang, Lei MD; Ma, Gang MD; Jin, Yunbo MD, PhD; Ye, Xiaoxiao MD; Qiu, Yajing MD; Chen, Hui MD, PhD; Yu, Wenxin MD; Yang, Xi MD; Hu, Xiaojie MD, PhD; Lin, Xiaoxi MD, PhD

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Abstract

Propranolol has been the first-line treatment for problematic infantile hemangioma (IH) since 2008. The recurrence of IHs after stopping treatment with propranolol was reported in several studies. Mechanisms underlying this phenomenon have not been elucidated so far. Our study is the first to show the general pathology of recurrence of IH after stopping treatment with propranolol. It can provide help for the clinical treatment of IHs.

Copyright © 2013 by Lippincott Williams & Wilkins

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