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March 2010 - - Issue 3
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Morris, Rhys J.; Woodcock, John P.
Annals of Surgery. 251(3):393-396, March 2010.
doi: 10.1097/SLA.0b013e3181b5d61c
A review was conducted of direct comparisons of the clinical effectiveness of intermittent pneumatic compression and graduated compression stockings in deep vein thrombosis prophylaxis. Of the 10 comparisons found, 5 included fewer than 40 patients, and showed no statistically significant difference, and 3 reported significantly lower deep vein thrombosis incidence with intermittent pneumatic compression.
Rubino, Francesco; Kaplan, Lee M.; Schauer, Philip R.; Cummings, David E.; on behalf of the Diabetes Surgery Summit Delegates
Annals of Surgery. 251(3):399-405, March 2010.
doi: 10.1097/SLA.0b013e3181be34e7
We report the position statement from the first International Conference on Gastrointestinal Surgery to Treat Type 2 Diabetes–(Diabetes Surgery Summit-DSS). This document embodies the foundations of diabetes surgery and recognizes the potential of surgery to advance the understanding and treatment of diabetes.
Caprini, Joseph A.
Annals of Surgery. 251(3):397-398, March 2010.
doi: 10.1097/SLA.0b013e3181d03ca2
DeMaria, Eric J.
Annals of Surgery. 251(3):406-408, March 2010.
doi: 10.1097/SLA.0b013e3181d03db5
Farrokhyar, Forough; Karanicolas, Paul J.; Thoma, Achilleas; Simunovic, Marko; Bhandari, Mohit; Devereaux, P. J.; Anvari, Mehran; Adili, Anthony; Guyatt, Gordon
Annals of Surgery. 251(3):409-416, March 2010.
doi: 10.1097/SLA.0b013e3181cf863d
This article reviews the significance of randomized controlled trials in the evaluation of surgical interventions, discusses some of the methodological challenges encountered in designing and conducting randomized controlled trials of surgical trials, and proposes possible solutions to overcome these challenges.
Kim, Hyung-Ho; Hyung, Woo Jin; Cho, Gyu Seok; Kim, Min Chan; Han, Sang-Uk; Kim, Wook; Ryu, Seung-Wan; Lee, Hyuk-Joon; Song, Kyo Young
Annals of Surgery. 251(3):417-420, March 2010.
doi: 10.1097/SLA.0b013e3181cc8f6b
Laparoscopic-assisted distal gastrectomy (LADG) is rapidly gaining in popularity. However, there is limited evidence regarding its oncologic safety. We conducted a phase III multicenter, prospective, randomized study comparing LADG with open gastrectomy. We found no significance difference in the morbidity and mortality between the LADG and open gastrectomy groups. Therefore, we conclude that this trial was safe and is thus ongoing.
Rouette, Justine; Trottier, Helen; Ducruet, Thierry; Beaunoyer, Mona; Lacroix, Jacques; Tucci, Marisa; for the Canadian Critical Care Trials Group
Annals of Surgery. 251(3):421-427, March 2010.
doi: 10.1097/SLA.0b013e3181c5dc2e
This is a subgroup analysis of the TRIPICU trial, addressing transfusion threshold in PICU's surgical patients. It suggests that a restrictive transfusion strategy is as safe as a liberal transfusion strategy for those patients.
Park, Sook Ryun; Kim, Min Ju; Ryu, Keun Won; Lee, Jun Ho; Lee, Jong Seok; Nam, Byung-Ho; Choi, Il Ju; Kim, Young-Woo
Annals of Surgery. 251(3):428-435, March 2010.
doi: 10.1097/SLA.0b013e3181ca69a7
Clinical stage is an independent predictor of long-term survival in the preoperative setting of resectable gastric cancer. It should be incorporated as a stratification factor in a randomized clinical trial of preoperative therapy.
Kiran, Ravi P.; da Luz Moreira, Andre; Remzi, Feza H.; Church, James M.; Lavery, Ian; Hammel, Jeffery; Fazio, Victor W.
Annals of Surgery. 251(3):436-440, March 2010.
doi: 10.1097/SLA.0b013e3181cf8814
Data from 3233 patients were retrospectively analyzed in a multivariable logistic regression model for septic complications after restorative proctocolectomy. Body mass index greater than 30, final pathologic diagnosis of ulcerative or Crohn's disease, perioperatiove transfusions, and surgeon were all independent factors associated with septic complications after restorative proctocolectomy.
Wexner, Steven D.; Coller, John A.; Devroede, Ghislain; Hull, Tracy; McCallum, Richard; Chan, Miranda; Ayscue, Jennifer M.; Shobeiri, Abbas S.; Margolin, David; England, Michael; Kaufman, Howard; Snape, William J.; Mutlu, Ece; Chua, Heidi; Pettit, Paul; Nagle, Deborah; Madoff, Robert D.; Lerew, Darin R.; Mellgren, Anders
Annals of Surgery. 251(3):441-449, March 2010.
doi: 10.1097/SLA.0b013e3181cf8ed0
The purpose of this study was to determine the safety and efficacy of SNS in a large population under the rigors of an FDA-approved investigational protocol. 133 patients underwent test stimulation with a 90% success rate, and 120 (110 females), of a mean age of 60.5 years and a mean FI duration of 6.8 years, received chronic implantation. Sacral nerve stimulation using IterStim Therapy is a safe and effective treatment for patients with FI.
Nitta, Hiroyuki; Sasaki, Akira; Fujita, Tomohiro; Itabashi, Hidenori; Hoshikawa, Koichi; Takahara, Takeshi; Takahashi, Masahiro; Nishizuka, Satoshi; Wakabayashi, Go
Annals of Surgery. 251(3):450-453, March 2010.
doi: 10.1097/SLA.0b013e3181cf87da
This study shows that laparoscopy-assisted major liver resections employing a hanging technique are safe and feasible and produce good short-term outcomes. The advantage of the method described in the present study is that it does not require any advanced laparoscopic techniques; thus liver surgeons can perform it easily.
Soubrane, Olivier; Brouquet, Antoine; Zalinski, Stéphane; Terris, Benoît; Brézault, Catherine; Mallet, Vincent; Goldwasser, François; Scatton, Olivier
Annals of Surgery. 251(3):454-460, March 2010.
doi: 10.1097/SLA.0b013e3181c79403
Seventy-eight patients with colorectal liver metastases and treated with oxaliplatin-based chemotherapy were retrospectively reviewed. Severe sinusoidal obstruction syndrome lesions were found in 59% of those and could be predicted using aspartate aminotransferase to platelet ratio index score. Severe sinusoidal obstruction syndrome lesions were associated with a worse postoperative outcome in patients undergoing major liver resection.
Takahashi, Hidenori; Ohigashi, Hiroaki; Ishikawa, Osamu; Eguchi, Hidetoshi; Gotoh, Kunihito; Yamada, Terumasa; Nakaizumi, Akihiko; Uehara, Hiroyuki; Tomita, Yasuhiko; Nishiyama, Kinji; Yano, Masahiko
Annals of Surgery. 251(3):461-469, March 2010.
doi: 10.1097/SLA.0b013e3181cc90a3
Serum CA19–9 alterations during preoperative gemcitabine-based chemoradiation therapy for resectable pancreatic cancer is a useful predictive indicator for differentiating between patients who would and would not benefit from subsequent resection 2 months after the initiation of preoperative treatment.
Poultsides, George A.; Reddy, Sushanth; Cameron, John L.; Hruban, Ralph H.; Pawlik, Timothy M.; Ahuja, Nita; Jain, Ajay; Edil, Barish H.; Iacobuzio-Donahue, Christine A.; Schulick, Richard D.; Wolfgang, Christopher L.
Annals of Surgery. 251(3):470-476, March 2010.
doi: 10.1097/SLA.0b013e3181cf8a19
IPMN-associated invasive adenocarcinoma of the pancreas has a more indolent behavior compared with standard pancreatic adenocarcinoma, as it typically presents at an earlier T stage and with an inherently lower rate of lymph node metastasis, poor differentiation, perineural and vascular invasion, and positive resection margin. In the presence of any of the aforementioned pathologic characteristics, however, outcomes after resection of IPMN-associated and standard pancreatic adenocarcinoma are not significantly different.
Partelli, Stefano; Castillo, Carlos Fernandez-Del; Bassi, Claudio; Mantovani, William; Thayer, Sarah P.; Crippa, Stefano; Ferrone, Cristina R.; Falconi, Massimo; Pederzoli, Paolo; Warshaw, Andrew L.; Salvia, Roberto
Annals of Surgery. 251(3):477-482, March 2010.
doi: 10.1097/SLA.0b013e3181cf9155
In the present study, we analyze the outcomes and survival of patients with invasive intraductal papillary mucinous neoplasms. Lymph node ratio and family history of pancreatic cancer are strong predictors of survival after resection for invasive intraductal papillary mucinous carcinoma.
Kanda, Mitsuro; Fujii, Tsutomu; Sahin, Tevfik T.; Kanzaki, Akiyuki; Nagai, Shunji; Yamada, Suguru; Sugimoto, Hiroyuki; Nomoto, Shuji; Takeda, Shin; Kodera, Yasuhiro; Morita, Satoshi; Nakao, Akimasa
Annals of Surgery. 251(3):483-487, March 2010.
doi: 10.1097/SLA.0b013e3181cf9171
To determine the implications of the invasion of the splenic vessels for prognosis in pancreatic body and tail cancer, we investigated the correlations between prognosis and the pathologic factors. Our results indicated that invasion of the splenic artery, but not that of the splenic vein, is a crucial prognostic factor.
Kaas, Reinoutje; Verhoef, Senno; Wesseling, Jelle; Rookus, Matti A.; Oldenburg, Hester S. A.; Peeters, Marie-Jeanne Vrancken; Rutgers, Emiel J. T.
Annals of Surgery. 251(3):488-492, March 2010.
doi: 10.1097/SLA.0b013e3181c3c36d
Bilateral or contralateral prophylactic mastecomy in 254 BRCA1/2 carriers resulted in only 1 postprophylactic incident breast cancer.
Kim, Hee Jeong; Park, Eun Hwa; Lim, Woo Sung; Seo, Jin Young; Koh, Beom Suk; Lee, Taik Jong; Eom, Jin Sup; Lee, Sung Wook; Son, Byung Ho; Lee, Jong Won; Ahn, Sei Hyun
Annals of Surgery. 251(3):493-498, March 2010.
doi: 10.1097/SLA.0b013e3181c5dc4e
Cosmetic issues associated with breast cancer surgery are important. The original SSM technique included removal of the gland and the nipple areola complex (NAC). However, the risk of tumor involvement of the NAC has been overestimated..
Heneghan, Helen M.; Miller, Nicola; Lowery, Aoife J.; Sweeney, Karl J.; Newell, John; Kerin, Michael J.
Annals of Surgery. 251(3):499-505, March 2010.
doi: 10.1097/SLA.0b013e3181cc939f
The development of clinically validated biomarkers for cancer has remained an insurmountable task despite other advances in the field of cancer molecular biology. We report that cancer-specific miRNAs are detectable and altered in the circulation of breast cancer patients; in particular, systemic miR-195 levels in breast cancer patients reflect many properties of an ideal biomarker.
Gronchi, Alessandro; Lo Vullo, Salvatore; Colombo, Chiara; Collini, Paola; Stacchiotti, Silvia; Mariani, Luigi; Fiore, Marco; Casali, Paolo Giovanni
Annals of Surgery. 251(3):506-511, March 2010.
doi: 10.1097/SLA.0b013e3181cf87fa
Quality of surgical margins independently predicts local control and survival. The effect on survival seems directly mediated by local recurrence to proximal sites invading the abdomen/thorax, and this may be the main way by which quality of surgery directly impacts the final prognosis of extremity soft tissue sarcoma patients.
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