| Editor-in-Chief: |
James C. Eisenach, M.D. |
| ISSN: |
0003-3022 |
| Online ISSN: |
1528-1175 |
| Frequency: |
12 issues per year |
| Ranking: |
1 of 26 in Anesthesiology |
| Impact Factor: |
5.486 |
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- Free Access
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Dubost, Clément; Le Gouez, Agnès; Jouffroy, Viridiana; Roger-Christoph, Sandrine; Benhamou, Dan; Mercier, Frédéric J.; Geeraerts, Thomas
Anesthesiology. 116(5):1066-1071, May 2012.
doi: 10.1097/ALN.0b013e318246ea1a
This study examined the use of ocular ultrasonography to estimate the incidence of raised intracranial pressure in patients with preeclampsia. Optic nerve sheath diameter (ONSD) measurements were compared in 26 preeclamptic and 25 healthy pregnant women. Median ONSD values were greater in preeclamptic patients compared with healthy pregnant women at delivery, 5.4 mm versus 4.5 mm. At delivery, 5 of 26 (19%) of preeclamptic patients had ONSD values above 5.8 mm whereas none of the healthy pregnant group had such high ONSD values. In the preeclamptic group, ONSD decreased after the third postpartum day and values at day 7 were not significantly different from those obtained in the normal pregnancy group. Further work is needed to confirm these findings and to better understand the diagnostic and therapeutic usefulness of ONSD.
Lellouche, François; Dionne, Stéphanie; Simard, Serge; Bussières, Jean; Dagenais, François
Anesthesiology. 116(5):1072-1082, May 2012.
doi: 10.1097/ALN.0b013e3182522df5
Optimal tidal volumes for mechanically ventilated patients without acute lung injury or acute respiratory distress syndrome remain controversial. In a cohort of 3,434 consecutive patients who underwent cardiac surgery, tidal volumes above 10 ml/kg are risks factors for organ failure.
Hakim, Sameh M.; Othman, Ahmed I.; Naoum, Dina O.
Anesthesiology. 116(5):987-997, May 2012.
doi: 10.1097/ALN.0b013e31825153cc
Risperidone or placebo was administered to 101 elderly patients who experienced subsyndromal delirium after cardiac surgery. Failure to treat subsyndromal delirium with risperidone was independently associated with a higher risk for clinical delirium.
Martina, Jerson R.; Westerhof, Berend E.; van Goudoever, Jeroen; de Beaumont, Edouard M. F. H.; Truijen, Jasper; Kim, Yu-Sok; Immink, Rogier V.; Jöbsis, Dorothea A.; Hollmann, Markus W.; Lahpor, Jaap R.; de Mol, Bas A. J. M.; van Lieshout, Johannes J.
Anesthesiology. 116(5):1092-1103, May 2012.
doi: 10.1097/ALN.0b013e31824f94ed
During cardiothoracic surgery, blood pressure was measured noninvasively and continuously with the Nexfin® monitor (BMEYE, Amsterdam, the Netherlands). With its physiological reconstruction methodology, values were comparable with invasive measurements over wide ranges of pressure changes.
Kuipers, Maria T.; Aslami, Hamid; Janczy, John R.; van der Sluijs, Koenraad F.; Vlaar, Alexander P. J.; Wolthuis, Esther K.; Choi, Goda; Roelofs, Joris J. T. H.; Flavell, Richard A.; Sutterwala, Fayyaz S.; Bresser, Paul; Leemans, Jaklien C.; van der Poll, Tom; Schultz, Marcus J.; Wieland, Catharina W.
Anesthesiology. 116(5):1104-1115, May 2012.
doi: 10.1097/ALN.0b013e3182518bc0
The NLRP3 inflammasome is an important innate immune receptor and mediates ventilator-induced lung injury. Mechanical ventilation up-regulates NLRP3 gene expression in human alveolar macrophages. NLRP3 inflammasome deficiency partially protects mice from ventilator-induced lung injury.
Yap, Steven C.; Lee, H. Thomas
Anesthesiology. 116(5):1139-1148, May 2012.
doi: 10.1097/ALN.0b013e31824f951b
Acute kidney injury leads to earlier onset of multiorgan dysfunction and increased mortality. In animal models, acute kidney injury results in distant organ injury through neutrophil migration, uncontrolled cytokine expression, and increased oxidative stress.
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Mind to Mind
The Mind to Mind section presents creative writing that explores the abstract side of our profession and our lives. “Anesthesia Checklist” challenges us to approach routine anesthetic tasks in a new way.
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