Skip Navigation LinksHome > February 2013 - Volume 118 - Issue 2 > Organ Transplantation: A Clinical Guide.
doi: 10.1097/ALN.0b013e31827bcdcd
Reviews of Educational Material

Organ Transplantation: A Clinical Guide.

Gillespie, Shane M M.S., D.O.

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Ever since the first successful human kidney transplant on identical twins in 1954, solid organ transplantation has made tremendous advancements in surgical technique. Concurrent with this, less toxic antimicrobial therapies and, more importantly, less toxic immunosuppressive therapies have become available. Because of these advancements, transplant recipients are living longer, with a better quality of life. As the life expectancy of transplant patients increases, physicians and other healthcare workers can expect to see more of these patients in their practices, for both surgical and nonsurgical medical care. A general understanding of solid organ transplantation and stem cell transplantation is imperative for today’s practicing clinician.
In each of its eight sections, Organ Transplantation: A Clinical Guide provides clinical information and guidance on a specific area of transplantation. The first section includes a historical introduction to transplant followed by a detailed description of immunological principles, including mechanisms of action, clinical effectiveness, clinical application, toxicity, and side effects. The first section ends with a broad overview of the major short-term and long-term complications facing organ transplant recipients. Sections two through seven discuss adult and pediatric heart, lung, liver, kidney, other abdominal organs (pancreas, intestine), and other types of transplants (face, stem cell, corneal). Section eight is the concluding chapter and covers legal and operational frameworks of transplantation in the United States, United Kingdom, and Europe. Each section is thorough and presented by experts in the respective field. The text includes helpful discussions related to recipient and donor selection, preoperative management, management during surgery, postoperative care, and early complications. Important topics involving the evaluation of living donors, brain death donors, and organ donation after cardiac death are also discussed.
There are multiple features that make this clinical guide unique. First, the book is written from a straightforward clinical perspective in such way that both clinicians and anyone involved in the transplantation process, even the general public, would be able to understand and benefit from it. Second, the book provides enough pertinent preoperative and postoperative clinical information and detail that it could be considered a go-to guide for those working in the surgical theater as a strong review of various transplantation techniques. Understanding and knowing what early and late complications to expect are paramount to providing good care. As a new cardiac anesthesiologist and critical care fellow who is personally involved perioperatively and postoperatively, this book has become the first resource I use when I am in need of a clinical refresher of a respective transplantation procedure. Overall, Organ Transplantation: A Clinical Guide provides a concise but comprehensive clinical review of all aspects of transplantation.
As organ transplantation continues to progress and outcomes continue to improve, as they have since the first successful kidney transplant, everyone who works in health care will be involved with these patients’ care at some level. Whether one is interested in a broad overview of the transplantation process, a detailed description of the most common expected complications, or what to expect perioperatively, this book is an effective reference. The size of the book is concise and compact and makes a good office reference, but it is too large to be considered a lab-coat style reference. The clinicians who would likely benefit the most from this clinical guide are residents, fellows, and new attendings.
Shane M. Gillespie, M.S., D.O.
, Mayo Clinic, Rochester, Minnesota.

© 2013 American Society of Anesthesiologists, Inc.

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