Skip Navigation LinksHome > November 1979 - Volume 51 - Issue 5 > Bupivacaine, 0.125 Per Cent, in Obstetric Epidural Analgesia...
Anesthesiology:
ORIGINAL ARTICLES: PDF Only

Bupivacaine, 0.125 Per Cent, in Obstetric Epidural Analgesia: Experience in Three Thousand Cases.

Bleyaert, A. M.D.; Soetens, M. M.D.; Vaes, L. M.D.; Van Steenberge, A. L. M.D.; der Donck, A. Van M.D.

Collapse Box

Abstract

Bupivacaine, 0.125 percent, with epinephrine, 1:800,000, was administered to 3,000 women in labor. Administration was in the lumbar epidural space for the purpose of achieving satisfactory analgesia with minimal or no motor paralysis. The usual initial dose of 12.5 mg (mean 13 +/- 2 SD) resulted in good sensory analgesia in 83 per cent of the patients and lasted for about an hour (mean 58 +/- 16 min). The mean total dose used for labor and delivery was 55 +/- 20 mg and the mean dose per hour 23 +/- 13 mg. Satisfactory analgesia for labor and delivery was obtained in 92 percent of the patients, and in 66 per cent there was no discernible motor blockade. In the 3,000 patients, there was no adverse reaction to bupivacaine or epinephrine. No patient had a total spinal block or neurologic sequelae, and no neonatal depression could be attributed to the anesthetic.
(C) 1979 American Society of Anesthesiologists, Inc.
Publication of an advertisement in Anesthesiology Online does not constitute endorsement by the American Society of Anesthesiologists, Inc. or Lippincott Williams & Wilkins, Inc. of the product or service being advertised.
Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.