Skip Navigation LinksHome > October 1969 - Volume 31 - Issue 4 > Myocardial Metabolism in Patients Having Aortic-valve Replac...
Anesthesiology:
Editorial Views: PDF Only

Myocardial Metabolism in Patients Having Aortic-valve Replacement.

Moffitt, Emerson A. M.D.; Rosevear, John W. M.D.; Townsend, Clary H. M.D.; McGoon, Dwight C. M.D.

Collapse Box

Abstract

Concentrations of metabolites and electrolytes in arterial and coronary sinus blood were studied in ten patients undergoing whole-body perfusion for aortic valve replacement. The study continued through three postoperative days. A comparison was made between five patients whose hearts were beating during perfusion and five whose hearts fibrillated. Oxygen consumption of the myocardium was reduced during hypothermic coronary perfusion; the reduction was greater in the beating hearts. Significant arterial-coronary sinus differences in electrolytes and osmolality were not seen. Arterial concentrations of energy metabolites utilized by the myocardium were elevated throughout operation, and all except glucose were utilized by the heart. Ketosis persisted after operation in the presence of above-normal glucose levels. Other than greater consumption of oxygen during perfusion, no consistent difference was seen between the performances of hearts that fibrillated and those that continued to beat.
(C) 1969 American Society of Anesthesiologists, Inc.
Publication of an advertisement in Anesthesiology Online does not constitute endorsement by the American Society of Anesthesiologists, Inc. or Lippincott Williams & Wilkins, Inc. of the product or service being advertised.
Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.