Ultrasound Assessment of the Prokinetic Effect of Erythromycin in Trauma Patients with a Full Stomach: A Case Series

Bouvet, Lionel MD, PhD; Boselli, Emmanuel MD, PhD; Cheere, Eugénie MSc; Stewart, Adrienne FRCA; Allaouchiche, Bernard MD, PhD; Chassard, Dominique MD, PhD

doi: 10.1213/ANE.0000000000001176
Critical Care, Trauma, and Resuscitation: Brief Report

In this preliminary prospective noninterventional study, we assessed the prokinetic effect of 3 mg•kg−1 erythromycin in nonfasted emergency trauma patients. Ultrasonographic measurements of the antral area were performed 30 minutes and immediately before the erythromycin infusion and serially at 30, 60, and 90 minutes after the start of the infusion. Gastric emptying rates before and after erythromycin infusion, and at each 30-minute period after erythromycin infusion, were then calculated. We found that gastric emptying rates were increased after erythromycin infusion although gastric content and volume remained similar.

From the *University of Lyon, Claude Bernard Lyon 1 University, Inserm, U1032, LabTau, and Department of Anesthesia and Intensive Care, Femme Mère Enfant Hospital, Hospices Civils de Lyon, Lyon, France; University of Lyon, Claude Bernard Lyon 1 University, and Department of Anesthesia and Intensive Care, Édouard Herriot Hospital, Hospices Civils de Lyon, Lyon, France; University of Lyon, Claude Bernard Lyon 1 University, and Department of Anesthesia and Intensive Care, Femme Mère Enfant Hospital, Hospices Civils de Lyon, Lyon, France; §Department of Anesthesia, University College London Hospitals NHS Foundation Trust, London, United Kingdom; and University of Lyon, Claude Bernard Lyon 1 University, Department of Intensive Care, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France.

Accepted for publication December 18, 2015.

Funding: None.

The authors declare no conflicts of interest.

Reprints will not be available from the authors.

Address correspondence to Lionel Bouvet, MD, PhD, Service d’Anesthésie Réanimation, Hospices Civils de Lyon, Groupement Hospitalier Est-Hôpital Femme Mère Enfant, 59 Blvd. Pinel, 69500 Bron, France. Address e-mail to lionel.bouvet@chu-lyon.fr.

© 2016 International Anesthesia Research Society