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Donor Difference (Living Versus Cadaver) Rather Than Preoperative Recipient's Status Affects Transfusion Requirements in Liver Transplantation

Kim, Gaab Soo MD; Gwak, Mi Sook MD; Ko, Justin Sang MD

Section Editor(s): Saidman, Lawrence

doi: 10.1213/
Letters to the Editor: Letters & Announcements

Department of Anesthesiology and Pain Medicine; Samsung Medical Center; Sungkyunkwan University School of Medicine; 50, Il won-Dong, Kangnam-Ku; Seoul, Korea 135-710;

Dr. Frasco does not wish to respond.

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To the Editor:

Frasco et al. (1) found significant differences in disease severity (Model for End-Stage Liver Disease, MELD score), impairment of coagulation function, and the need for red blood cell and component transfusion between patients undergoing living and cadaveric liver transplantation. We performed a similar study which was published in Korean (2), although it appeared as an abstract in English (3). In our study, 17 patients received a cadaveric liver and 16 patients received a liver from a living donor. In contrast to the results of Frasco et al. study, we found no significant differences in the preoperative MELD score (P = 0.544, Student's t-test) or coagulation function between the groups, as shown in Table 1. We believe that the type of donor liver (living versus cadaver) rather than the recipient's preoperative status is a better predictor of reperfusion coagulopathy and intraoperative transfusion requirements.

Gaab Soo Kim, MD

Mi Sook Gwak, MD

Justin Sang Ko, MD

Department of Anesthesiology and Pain Medicine

Samsung Medical Center

Sungkyunkwan University School of Medicine

50, Il won-Dong, Kangnam-Ku

Seoul, Korea 135-710

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1. Frasco P, Poterack K, Hentz J, Mulligan D. A comparison of transplantation requirements between living donation and cadaveric donation liver transplantation: relationship to model of end-stage liver disease score and baseline coagulation status. Anesth Analg 2005;101:30–7
2. Shin BS, Ha IH, Kim GS, Gwak MS, Chung IS. The comparison of coagulation status in the cadaveric donor and living-related liver transplantation. Kor J Anesth 2002;43:49–57
3. Baek H, Shin B, Kim G. The comparison of coagulation status in the cadaveric donor and living-ralated liver transplantation. Anesthesiology 2004;101:A1288
© 2007 International Anesthesia Research Society