Abdominal Girth, Vertebral Column Length, and Spread of Spinal Anesthesia in 30 Minutes after Plain Bupivacaine 5 mg/mL

Zhou, Qing-he MD; Xiao, Wang-pin MD; Shen, Ying-yan MD

doi: 10.1213/ANE.0000000000000199
Regional Anesthesia: Research Report

BACKGROUND: The spread of spinal anesthesia is highly unpredictable. In patients with increased abdominal girth and short stature, a greater cephalad spread after a fixed amount of subarachnoidally administered plain bupivacaine is often observed. We hypothesized that there is a strong correlation between abdominal girth/vertebral column length and cephalad spread.

METHODS: Age, weight, height, body mass index, abdominal girth, and vertebral column length were recorded for 114 patients. The L3-L4 interspace was entered, and 3 mL of 0.5% plain bupivacaine was injected into the subarachnoid space. The cephalad spread (loss of temperature sensation and loss of pinprick discrimination) was assessed 30 minutes after intrathecal injection. Linear regression analysis was performed for age, weight, height, body mass index, abdominal girth, vertebral column length, and the spread of spinal anesthesia, and the combined linear contribution of age up to 55 years, weight, height, abdominal girth, and vertebral column length was tested by multiple regression analysis.

RESULTS: Linear regression analysis showed that there was a significant univariate correlation among all 6 patient characteristics evaluated and the spread of spinal anesthesia (all P < 0.039) except for age and loss of temperature sensation (P > 0.068). Multiple regression analysis showed that abdominal girth and the vertebral column length were the key determinants for spinal anesthesia spread (both P < 0.0001), whereas age, weight, and height could be omitted without changing the results (all P > 0.059, all 95% confidence limits < 0.372).

CONCLUSIONS: Multiple regression analysis revealed that the combination of a patient’s 5 general characteristics, especially abdominal girth and vertebral column length, had a high predictive value for the spread of spinal anesthesia after a given dose of plain bupivacaine.

Published ahead of print May 7, 2014

From the Department of Anesthesiology, the Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China.

Accepted for publication January 10, 2014.

Published ahead of print May 7, 2014

Funding: This work was supported by the second affiliated hospital of Jiaxing University.

The authors declare no conflicts of interest.

Reprints will not be available from the authors.

Address correspondence to Wang-pin Xiao, MD, Department of Anesthesiology, the Second Affiliated Hospital of Jiaxing University, Jiaxing, Zhejiang Province, China. Address e-mail to jxanesthesia@163.com.

© 2014 International Anesthesia Research Society