ANESTHESIA, as a phenomenon of asphyxiation, has been known since the ancients. The fact, however, that men become unconscious and suffer loss of pain on sensory stimulation has' not so long been known to be dependent upon lack of oxygen alone. If one searches the older literature, all the evidences along our theme are found under the head of asphyxia and suffocation. The usual asphyxial condition, as in drowning or hanging or other methods of suppressing respiration, is not a simple case of oxygen want. The factor of carbon dioxid accumulation is always associated. The separation of these two conditions is absolutely necessary to attribute to each its proper value.
© 1922 International Anesthesia Research Society