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Advances in Anatomic Pathology:
doi: 10.1097/PAP.0b013e31821697f5
Book Review

Review of Kradin

Renshaw, Andrew MD

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Author Information

Baptist Hospital Miami, FL

Review of Kradin


Title: Diagnostic Pathology of Infectious Disease

Author: Richard L. Kradin, MD

Affiliation: Department of Pathology, Harvard Medical School, Associate Pathologist and Associate Physician, Pulmonary/Critical Care Unit, Massachusetts General Hospital, Boston, MA

Publishers: Saunders Elsevier

Year/City/ISBN: 2010/Philadelphia/978-1-4160-3429-2

Organization: By organ system

Readability: Detailed

Pictures: Extensive, including images of rare lesions

Strengths: Fully comprehensive summary of infectious disease in surgical pathology

Weakness: Uneven chapter quality

Price: $199

Pages: 642


This book surprised me. Like many surgical pathologists, I am more of a tumor pathologist than an infectious disease pathologist. Nevertheless, I have certainly seen a wide variety of infections under the microscope, and I did not think that Dr Kradin would be able to bring much that was new to the field of the morphology of infectious disease, and I would never have bet that an entire book could be written on the subject. However, Dr Kradin has managed to put enough new things into this text to make me concede my initial impression was wrong.

The book is truly comprehensive, and includes the entire spectrum of infectious disease, covered both in general and by organ system. Although there are numerous images of infections that we see every day, there are also a large number of images of infections that most surgical pathologist rarely see if ever, including smallpox, rheumatic fever, and Hantavirus. The chapter on skin infections includes numerous photomicrographs of all the different stages/morphologies of leprosy. As a resource for diagnostic images of the pathology of very rare infections, this book is worth the price.

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Dr Kradin examines infections from a wide variety of perspectives. In addition to a broad overview and chapters devoted to infections of each organ system, the book also includes an entire chapter devoted to the ultrastructure of infectious disease.

The field of diagnostic infectious disease is changing, and most of the new tests use molecular methods to diagnose disease. Certainly, the majority of infections today are diagnosed in the microbiology or molecular laboratory, and not by the surgical pathologist sitting at his or her microscope. As a result, the diagnosis of infectious disease from morphology is a field that may be mature, and practitioners like Dr Kradin may be a resource that will become rare with the passage of time and new generations. If this is so, then Dr Kradin's textbook is an even more valuable resource for the practicing pathologist that may not be superceded anytime soon.

Andrew Renshaw, MD

Baptist Hospital Miami, FL

© 2011 Lippincott Williams & Wilkins, Inc.


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