Skip Navigation LinksHome > March 2013 - Volume 20 - Issue 2 > Next-generation Sequencing Discoveries in Lymphoma
Advances in Anatomic Pathology:
doi: 10.1097/PAP.0b013e3182862724
Review Articles

Next-generation Sequencing Discoveries in Lymphoma

Slack, Graham W. MD; Gascoyne, Randy D. MD

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Abstract

Since the mapping of the human genome and the advent of next-generation sequencing technology thorough examination of the cancer genome has become a reality. Over the last few years several studies have used next-generation sequencing technology to investigate the genetic landscape of Hodgkin and non-Hodgkin lymphomas, identifying novel genetic mutations and gene rearrangements that have shed new light on the underlying tumor biology in these diseases as well as identifying possible targets for directed therapy. This review covers the major discoveries in lymphoma using next-generation sequencing technology.

© 2013 Lippincott Williams & Wilkins, Inc.

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