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Cutaneous Soft Tissue Tumors That Make You Say, Oh $*&%!

Patel, Rajiv M. MD*; Billings, Steven D. MD

Advances in Anatomic Pathology:
doi: 10.1097/PAP.0b013e31826661d1
Review Articles

Subsets of cutaneous soft tissue tumors present morphologic features which are diagnostically challenging in part because of their ability to obscure the ultimate nature of the underlying neoplastic process. This review discusses entities, which in the authors’ experience, present such challenges. The clinical, histologic, immunohistochemical, and where appropriate, molecular features of these entities are discussed along with their prognosis and differential diagnosis.

Author Information

*Department of Pathology and Dermatology, University of Michigan, Ann Arbor, MI

Department of Anatomic Pathology and Dermatology, Cleveland Clinic, Cleveland, OH

The authors have no funding or conflicts of interest to disclose.

Reprints: Steven D. Billings, MD, Department of Anatomic Pathology and Dermatology, Cleveland Clinic, 9500 Euclid Avenue L25, Cleveland, OH 44195 (e-mail: figures can be viewed online in color at http://

© 2012 Lippincott Williams & Wilkins, Inc.