Skip Navigation LinksHome > January 2012 - Volume 19 - Issue 1 > Napsin A Expression in Lung and Kidney Neoplasia: A Review...
Advances in Anatomic Pathology:
doi: 10.1097/PAP.0b013e31823e472e
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Napsin A Expression in Lung and Kidney Neoplasia: A Review and Update

Ordóñez, Nelson G. MD

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Abstract

Napsin A is an aspartic protease present in the epithelial cells of the lung and kidney. Recent studies have shown that, in lung tumors, napsin A expression is restricted to lung adenocarcinomas, whereas among renal tumors, it is frequently expressed in renal cell carcinomas, especially the papillary and clear cell subtypes. Owing to its restricted expression, napsin A is a useful marker that can assist in the diagnosis of both lung adenocarcinomas and renal cell carcinomas.

© 2012 Lippincott Williams & Wilkins, Inc.

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