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Malignant Biphasic Tumors of the Lungs

Weissferdt, Annikka MD; Moran, Cesar A. MD

Advances in Anatomic Pathology: May 2011 - Volume 18 - Issue 3 - p 179–189
doi: 10.1097/PAP.0b013e318216980c
Review Articles

Malignant biphasic tumors of the lungs are rare primary tumors of the bronchopulmonary system. These tumors are composed of malignant epithelial and mesenchymal elements and together comprise <2% of all primary pulmonary neoplasms. The tumors belonging to this group include pulmonary blastoma, pleuropulmonary blastoma, and carcinosarcoma. In this study, the clinicopathologic features, immunohistochemical phenotype, molecular biological characteristics, and the differential diagnosis of these uncommon neoplasms are discussed.

Department of Pathology, MD Anderson Cancer Center, Houston, TX

Reprints: Annikka Weissferdt, MD, Department of Pathology, MD Anderson Cancer Center, Houston, TX 77030 (e-mail: aweissferdt@doctors.org.uk).

All figures can be viewed online in color at http://www.anatomicpathology.com.

© 2011 Lippincott Williams & Wilkins, Inc.