Adenocarcinoma of the Upper Aerodigestive TractStelow, Edward B. MD*; Mills, Stacey E. MD*; Jo, Vickie Y. MD*; Carlson, Diane L. MD†Advances in Anatomic Pathology: July 2010 - Volume 17 - Issue 4 - pp 262-269 doi: 10.1097/PAP.0b013e3181e3bf80 Review Articles Abstract Author Information Although squamous cell carcinoma is the most frequent malignant diagnosis made with upper aerodigestive tract specimens, a myriad of neoplasms can occur throughout the area. Very uncommonly, one encounters adenocarcinomas that cannot be better classified as salivary gland-type neoplasia. This manuscript reviews these tumors, including sinonasal intestinal-type adenocarcinomas, sinonasal low-grade and high-grade nonintestinal adenocarcinomas and nasopharyngeal papillary adenocarcinomas. Clinical, histologic, and immunohistochemical features and differential diagnoses are discussed. *Department of Pathology, University of Virginia, Charlottesville, VA †Cleveland Clinic Florida, Department of Lab Medicine and Pathology, Weston, FL Reprints: Diane L. Carlson, MD, Cleveland Clinic Florida, Department of Lab Medicine and Pathology, 3100 Weston Rd, Weston, FL 33331 (e-mail: firstname.lastname@example.org). All figures can be viewed online in color at http://www.anatomicpathology.com © 2010 Lippincott Williams & Wilkins, Inc.