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The Expanding Family of Glioneuronal Tumors

Allende, Daniela S. MD; Prayson, Richard A. MD

Advances in Anatomic Pathology:
doi: 10.1097/PAP.0b013e3181915e3b
Review Articles

Three new entities have been recently added to the group of glioneuronal tumors in the most recent update of the World Health Organization classification of tumors of the central nervous system: papillary glioneuronal tumor, rosetted glioneuronal tumor with neuropil-like islands, and rosette-forming glioneuronal tumor of the fourth ventricle. These tumors are relatively infrequent lesions, and because of that, they can be challenging to diagnose for the practicing pathologist. In this article, we summarize the clinical and pathologic findings of these new lesions.

Author Information

Department of Anatomic Pathology, Cleveland Clinic Foundation, Cleveland, OH

Correspondence: Richard Prayson, MD, Department of Anatomic Pathology, The Cleveland Clinic, L25, 9500 Euclid Avenue, Cleveland, OH 44195 (e-mail:

All figures can be viewed online in color at

© 2009 Lippincott Williams & Wilkins, Inc.