Skip Navigation LinksHome > July 2003 - Volume 10 - Issue 4 > Collagen-Rich Tumors of Soft Tissues: An Overview
Text sizing:
A
A
A
Advances in Anatomic Pathology:
Review Articles

Collagen-Rich Tumors of Soft Tissues: An Overview

Nielsen, G. Petur*; O'Connell, John X.†; Wehrli, Bret M.‡; Rosenberg, Andrew E.*

Supplemental Author Material
Collapse Box

Abstract

Although relatively common, soft tissue tumors frequently present diagnostic problems for practicing pathologists. Immunohistochemistry has facilitated the diagnosis of many mesenchymal tumors; however, there is considerable overlap in the staining profiles among cells demonstrating fibroblastic and myofibroblastic differentiation. It has been our experience that soft tissue tumors associated with abundant extracellular collagen deposition commonly cause problems in classification. One reason for this is that tumors displaying this morphology include representatives from different histogenetic families. Specifically, tumors exhibiting fibroblastic, myofibroblastic and even lipomatous differentiation may manifest as a densely collagenous mass. It is the purpose of this review to highlight these collagen-rich soft tissue tumors.

© 2003 Lippincott Williams & Wilkins, Inc.

Login

Article Tools

Share

Search for Similar Articles
You may search for similar articles that contain these same keywords or you may modify the keyword list to augment your search.