Skip Navigation LinksHome > August 2010 - Volume 340 - Issue 2 > Hypokalemic Thyrotoxic Periodic Paralysis With Thyrotoxic Ps...
American Journal of the Medical Sciences:
doi: 10.1097/MAJ.0b013e3181cbf567
Grand Rounds Contributor: Case Report/Focused Review

Hypokalemic Thyrotoxic Periodic Paralysis With Thyrotoxic Psychosis and Hypercapnic Respiratory Failure.

Abbasi, Bushra MD; Sharif, Zain MD; Sprabery, Laurie R. MD

Section Editor(s): Lopez, Fred A. MD

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Abstract

Thyrotoxic periodic paralysis is a rare and potentially lethal neuromuscular disease that manifests as recurrent episodic muscle weakness associated with hypokalemia and thyrotoxicosis. Paralysis can rarely involve respiratory muscles leading to acute respiratory failure. The disease primarily affects people of Asian descent, but it is being increasingly reported in other ethnic groups. We review the literature and report a case of hypokalemic thyrotoxic periodic paralysis manifesting as thyroid storm with episodic acute respiratory failure requiring recurrent intubation and eventually requiring thyroidectomy for resolution of symptoms.

© Copyright 2010 Southern Society for Clinical Investigation

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