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Undiagnosed Primary Cardiac Liposarcoma in an Adult: A Case Report and Review of the Literature

Papavdi, Asteria MD, PhD; Agapitos, Emmanouil MD

American Journal of Forensic Medicine & Pathology: December 2013 - Volume 34 - Issue 4 - p 299–301
doi: 10.1097/PAF.0b013e31828cff50
Case Reports

Abstract: Well-differentiated liposarcomas are locally aggressive malignant mesenchymal neoplasms, which rarely metastasize to the heart and pericardium. Primary cardiac liposarcomas are extremely rare as well, and in both instances, symptoms are difficult to recognize. Therefore, accurate antemortem diagnosis seldom happens. A rare case of an undiagnosed, primary, well-differentiated cardiac liposarcoma is presented, in a 67-year-old man who suffered a sudden cardiac death. The tumor seemed to arise from the epicardium of the left ventricle and expand into the myocardium of the left ventricle and intraventricular septum. Macroscopic and histopathological findings are presented, as well as a short review of current literature.

From the Department of Pathology, National and Kapodistrian University of Athens, Athens, Greece.

Manuscript received April 20, 2012; accepted July 30, 2012.

The authors report no conflicts of interest.

Reprints: Asteria Papavdi, MD, PhD, Department of Pathology, National and Kapodistrian University of Athens, Athens, Greece. E-mail: apapavdi7@gmail.com.

© 2013 by Lippincott Williams & Wilkins.