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Sudden Cardiac Death Due to an Anomalous Posterior Papillary Muscle

Cittadini, Francesca MD, PhD*; Oliva, Antonio MD, PhD*; Arena, Vincenzo MD†; Minelli, Natalia MD*; Pascali, Vincenzo L. MD, PhD*

American Journal of Forensic Medicine & Pathology:
doi: 10.1097/PAF.0b013e3181d3ca7e
Case Reports
Abstract

Anomalies of the mitral subvalvular apparatus can include differing types of papillary muscles and chordae tendinae. Direct insertion of the anomalous papillary muscle or chordae tendinea into the anterior mitral leaflet and fusion to the ventricular septum are common findings related to these anomalies. Anomalous papillary muscles or chordae, especially those that insert directly into the mitral leaflets, play a role in obstructing left ventricular outflow by restricting the mobility of the leaflets and/or tethering them toward the septum, thus narrowing the left ventricular outflow tract (LVOT). The incidence of mitral valve anomalies associated with LVOT is probably underestimated. This topic is frequently studied, however, especially in the pediatric cardiac surgery milieu, because LVOT obstruction could have a surgical solution. We report a case of an 18-year-old woman affected by epilepsy since 5 months of age who was found dead in her bedroom. An uncommon anomalous papillary muscle/chordae was the main autopsy finding. This malformation causes direct continuity between an accessory papillary muscle and a mitral leaflet, resulting in a long rigid area that can cause dynamic late-systolic intraleft-ventricular obstruction. In our case, in the absence of any other pathologic findings or major structural abnormalities, we speculate that a malignant cardiac arrhythmia provoked by the accessory papillary muscle could be the cause of death.

Author Information

From the *Institute of Forensic Medicine, and †Institute of Pathology, Catholic University, School of Medicine, Rome, Italy.

Manuscript received January 23, 2009; accepted August 5, 2009.

The authors report no conflicts of interest.

Supplemental digital contents are available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal's Web site (www.amjforensicmedicine.com).

Reprints: Francesca Cittadini, MD, PhD, Institute of Forensic Medicine, Catholic University, School of Medicine, Rome, Italy. E-mail: francesca.cittadini@rm.unicatt.it.

© 2011 by Lippincott Williams & Wilkins.